9 Best Baby Formula For Gas | Comfort for Tiny Tummies

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Fast, proven relief for fussiness, gas, and spit-up in a day.

This formula is designed to ease fussiness, crying, gas, and spit-up within 24 hours, a promise that shows up in the reviews. It uses smaller, broken-down proteins that are easier for sensitive tummies to digest, along with a patented prebiotic blend of PDX & GOS to support softer, more regular stools.

The brain-building DHA and choline are included for support during the first year, and the HuMO6 blend adds essential vitamins and minerals for immune health. Parents note it’s gentle even on tiny bellies born under 5 pounds, which is where gas issues often start.

The 35.2-ounce refill box is one of the larger sizes here, giving you strong value per feeding. With a 4.7-star average across 679 ratings, this is the second most popular pick in our list and the one parents describe as their “go to.”

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The allergy-level relief that stops colic when other formulas fail.

This formula stands out because its prebiotic fiber blend (GOS/FOS—types of fiber that feed good gut bacteria) mimics those in breast milk, and it adds DHA and ARA (omega-3 and omega-6 fatty acids that support brain and eye development). Parents who tried nine other formulas before this one say it finally stopped projectile vomiting and diarrhea. Another reports “No more colic, gas or upset tummy” and a baby who finally sleeps through the night.

It’s the most expensive formula here per ounce, which is the main trade-off. The 4.6-star average across 455 ratings shows that for babies with true protein sensitivity, the price is worth it. Rated #1 best tasting hypoallergenic formula by parents in a 2024 nationwide taste test.

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The hospital-trusted hypoallergenic formula with an immune-boosting twist.

Similac is the #1 infant formula brand fed in hospitals, and Alimentum is its answer for food allergies and colic caused by protein sensitivity. The milk protein is broken down into tiny pieces to virtually eliminate allergic reactions in most babies who are allergic to cow’s milk protein. It starts reducing colic symptoms within 24 hours in most infants.

It’s the first and only hypoallergenic formula with 2′-FL HMO, an immune-nourishing ingredient, and it skips palm olein oil to help reduce constipation and gas. One owner sums it up: “very gentle on their stomachs and they seem to like the taste.” Others note the proteins are already broken down, which helps babies who have a hard time digesting intact proteins.

There’s also a ready-to-feed version for late-night and on-the-go feeding with no mixing required. The 4.6-star average across 602 ratings is strong, though the value gets mixed reviews at this price point.

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The name-brand rival that gently tackles gas without the price tag.

This powder is designed to cut down on fussiness, gas, and crying by being gentle on tiny, tender tummies and easier to digest. Its nutrition matches Enfamil NEUROPRO Gentlease directly—parents noticed the similarity, with one reporting “Hardly noticed a difference to Enfamil formula,” while another says they stuck with it for 10 months with zero problems.

It contains DHA for brain support, choline for development, and 2′-FL HMO for immune health, with no artificial growth hormones and no GMOs. It’s also gluten-free and certified kosher by the Orthodox Union. The 21.5-ounce tub has a built-in spot to store the scoop, a small detail parents appreciate.

At 4.6 stars across 595 ratings, this is one of the higher-value picks. The mixed reviews on digestibility are note — some babies improved, while a few got fussier or constipated, so watch your little one’s reaction closely.

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The lactose-light formula that protects the wallet and the tummy.

If lactose is the problem, this powder cuts it by 99 percent compared to standard milk-based formula, targeting fussiness and gas head-on. It provides complete nutrition for babies 0-12 months and compares to Similac Pro-Sensitive, but at a fraction of the cost. One owner describes it as “the best deal for lactose-sensitive formulas” and notes it “works as good as more expensive brands and mixes better.”

The 2′-FL HMO prebiotic aids growth of beneficial bacteria in the digestive tract for immune support, while DHA supports brain and eye development. It’s non-GMO with no artificial growth hormones. The 22.5-ounce tub is a good mid-size option, letting you test whether reduced lactose is the fix before committing to a bigger buy.

With a 4.3-star average across 334 ratings, it’s the budget pick that works for many lactose-sensitive babies — though a portion of buyers report it didn’t help their baby’s gas, so keep expectations realistic.

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The organic gentle formula that swaps corn syrup for real lactose.

Formulated with smaller milk proteins to support digestion and help reduce fussiness, gas, and tears, Bobbie uses 100 percent lactose just like breast milk. Corn syrup, maltodextrin, and sucrose aren’t in human milk, so they aren’t in this formula — a stance parents appreciate. It’s USDA and EU Organic plus Clean Label Project Certified.

The results speak clearly: parents report “no more gassy cries or scrunching,” a noticeable reduction in spit-up, and regular bowel movements. One owner noted their baby accepted it like breast milk with no post-feed fuss, which is the ideal outcome for a gentle formula. Each batch goes through over 2,000 quality checks.

At 4.5 stars across 331 ratings, it’s a solid pick, though the 14.1-ounce can is smaller than most, which affects value. Some parents find the price reasonable for organic; others consider it pricey.

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The whey-based formula that breastfed babies transition into smoothly.

Built with 100% whey protein, this formula avoids the curdling that casein protein can cause, making it uniquely gentle on sensitive tummies. Its advanced 2-step hydrolysis process breaks down proteins so they’re easy to digest, and the added probiotic B. Lactis — a tummy-friendly probiotic like those found in breastmilk — supports gut health.

This formula is designed to promote easy digestion and softer poops compared to intact protein formulas (those with full-length proteins that are harder to break down), which is why parents call it “the best formula for constipated babies.” One owner loved it for combo feeding a breastfed baby and noted it’s one of the best-rated formulas on Consumer Reports. Another report: “Only formula both of my kiddos could manage,” including a child with a dairy allergy.

It’s the only baby formula with a blend of DHA, HMOs, and probiotics for infants aged 0-12 months. At 4.4 stars across 100 ratings, the count is smaller than other picks, but the feedback from combo-feeding families is remarkably consistent.

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The organic A2 milk formula that’s gentle on bellies and budgets.

Made with A2 organic milk, this formula uses a beta-casein protein found naturally in mammal milks, including breast milk. By sourcing milk from cows that predominantly produce A2 beta-casein proteins, it’s gentle on bellies and easy to digest — a real advantage for babies who react to standard A1 cow’s milk. The proprietary organic fat blend of organic oils and A2 organic milk keeps the recipe easy on digestion.

It contains no corn syrup, palm oil, GMOs, artificial colors, sweeteners, or growth hormones. Parents describe it as “the most affordable organic formula I’ve found” and note “I don’t notice any gas or digestive issues.” Every batch is crafted in small batches at a facility in Ohio with rigorous quality checks.

At 4.6 stars across 399 ratings, it’s a quality pick. Note the mixed feedback on digestibility — most babies thrive, but some became constipated, which is a risk with any new formula.